SRGN Antikörper (Middle Region)

Produktnummer ABIN2778809

Produktdetails anti-SRGN Antikörper

Target: SRGN (serglycin (SRGN))

Bindungsspezifität: Middle Region

Reaktivität: Human, Kaninchen, Ratte, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SRGN Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RTDLFPKTRI QDLNRIFPLS EDYSGSGFGS GSGSGSGSGS GFLTEMEQDY

Homologie: Guinea Pig: 78%, Horse: 100%, Human: 100%, Pig: 91%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SRGN. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SRGN

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 158 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SRGN

Target: SRGN (serglycin (SRGN))

Andere Bezeichnung: SRGN (SRGN Produkte)

Synonyme: PPG antikoerper, PRG antikoerper, PRG1 antikoerper, Prg antikoerper, Prg1 antikoerper, Sgc antikoerper, Pgsg antikoerper, serglycin antikoerper, SRGN antikoerper, Srgn antikoerper

Hintergrund: SRGN is a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. SRGN was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis.This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: FLJ12930, MGC9289, PPG, PRG, PRG1
Protein Interaction Partner: UBQLN1, SGTA, UBQLN4, PSRC1, CEP70, UBR4, BAG6, CCL3, PF4, GZMB, CD44, ALB,
Protein Size: 158

Molekulargewicht: 18 kDa

Gen-ID: 5552

NCBI Accession: NM_002727, NP_002718

UniProt: P10124

Pathways: Maintenance of Protein Location