PPP1R8 Antikörper (Middle Region)

Produktnummer ABIN2778806

Dieses Anti-PPP1R8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von PPP1R8 in WB und IHC. Geeignet für Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für PPP1R8 Antikörper (Middle Region) (ABIN2778806)

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPP1R8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PPP1R8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PNLAPDVDLT PVVPSAVNMN PAPNPAVYNP EAVNEPKKKK YAKEAWPGKK

Spezifität: This antibody recognizes isoform-gamma

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against PPP1R8. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPP1R8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 127 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPP1R8

Target: PPP1R8 (Protein Phosphatase 1, Regulatory Subunit 8 (PPP1R8))

Andere Bezeichnung: PPP1R8

Hintergrund: This gene, through alternative splicing, encodes three different isoforms. Two of the protein isoforms encoded by this gene are specific inhibitors of type 1 serine/threonine protein phosphatases and can bind but not cleave RNA. The third protein isoform lacks the phosphatase inhibitory function but is a single-strand endoribonuclease comparable to RNase E of E. coli. This isoform requires magnesium for its function and cleaves specific sites in A+U-rich regions of RNA.
Alias Symbols: ARD1, ARD-1, NIPP1, NIPP-1, PRO2047
Protein Interaction Partner: APPBP2, UBC, FBXO25, HMGA1, WDR77, CTNNBL1, PPIL1, PPP1CC, PPP1CA, NF2, APP, SF3A2, Cep72, PPP1CB, SUZ12, RBBP4, EZH2, EED, RBM48, SF3B1, SETDB1, MELK, HDAC2, C14orf1, STC2, CDC5L, CRMP1, PRKACA, GBP2, LYN, CSNK2A2, CSNK2A1, NME2,
Protein Size: 127

Molekulargewicht: 14 kDa

Gen-ID: 5511

NCBI Accession: NM_002713, NP_002704

UniProt: Q12972