PIGF Antikörper (N-Term)

Produktnummer ABIN2778804

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PIGF in IHC und WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Schaf.Es wurde in 1 Publikation zitiert.

Kurzübersicht für PIGF Antikörper (N-Term) (ABIN2778804)

Target: PIGF (Phosphatidylinositol Glycan F (PIGF))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PIGF Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails anti-PIGF Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PIGF Antibody - N-terminal region

Sequenz: MKDNDIKRLL YTHLLCIFSI ILSVFIPSLF LENFSILETH LTWLCICSGF

Homologie: Cow: 86%, Dog: 93%, Horse: 92%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%, Sheep: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against PIGF. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PIGF

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8108025

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PIGF Antikörper (ABIN2778804)

Mohammed, Nasreen, Tepper, Antony: "Cyclic stretch induces PlGF expression in bronchial airway epithelial cells via nitric oxide release." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 292, Issue 2, pp. L559-66, (2007) (PubMed).

Details zu PIGF

Target: PIGF (Phosphatidylinositol Glycan F (PIGF))

Andere Bezeichnung: PIGF

Hintergrund:

Background Information: PIGF is a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. PIGF and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described.

Gene Name: Phosphatidylinositol glycan anchor biosynthesis, class F

Alternative Symbols: MGC32646, MGC33136

Protein Name: Phosphatidylinositol-glycan biosynthesis class F protein

Molekulargewicht: 25kDa

Gen-ID: 5281

NCBI Accession: NP_002634

UniProt: Q07326

Pathways: Inositol Metabolic Process