ISG20 Antikörper (N-Term)

Produktnummer ABIN2778795

Dieser Anti-ISG20 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von ISG20 in WB. Geeignet für Human, Ratte, Maus, Hund, Pferd, Rind (Kuh), Schwein, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für ISG20 Antikörper (N-Term) (ABIN2778795)

Target: ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Rind (Kuh), Schwein, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ISG20 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ISG20 Antikörper

Bindungsspezifität: N-Term

Sequenz: GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 181 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ISG20 Antikörper (ABIN2778795)

Zahoor, Xue, Sato, Murakami, Takeshima, Aida: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).

Horio, Murai, Inoue, Hamasaki, Tanaka, Ohgi: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." in: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).

Details zu ISG20

Target: ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Andere Bezeichnung: ISG20

Hintergrund: ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
Alias Symbols: CD25, HEM45
Protein Interaction Partner: UBC,
Protein Size: 181

Molekulargewicht: 20 kDa

Gen-ID: 3669

NCBI Accession: NM_002201, NP_002192

UniProt: Q96AZ6