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ISG20 Antikörper (N-Term)

Dieses Anti-ISG20-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ISG20 in WB. Geeignet für Human, Ratte, Maus, Hund, Pferd, Rind (Kuh), Schwein, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.
Produktnummer ABIN2778795

Kurzübersicht für ISG20 Antikörper (N-Term) (ABIN2778795)

Target

Alle ISG20 Antikörper anzeigen
ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

Reaktivität

Human, Ratte, Maus, Hund, Pferd, Rind (Kuh), Schwein, Meerschweinchen, Kaninchen

Wirt

  • 20
  • 5
Kaninchen

Klonalität

  • 22
  • 3
Polyklonal

Konjugat

  • 20
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser ISG20 Antikörper ist unkonjugiert

Applikation

  • 24
  • 11
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    GAVLYDKFIR PEGEITDYRT RVSGVTPQHM VGATPFAVAR LEILQLLKGK

    Homologie

    Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against ISG20. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human ISG20
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 181 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Zahoor, Xue, Sato, Murakami, Takeshima, Aida: "HIV-1 Vpr induces interferon-stimulated genes in human monocyte-derived macrophages." in: PLoS ONE, Vol. 9, Issue 8, pp. e106418, (2014) (PubMed).

    Horio, Murai, Inoue, Hamasaki, Tanaka, Ohgi: "Crystal structure of human ISG20, an interferon-induced antiviral ribonuclease." in: FEBS letters, Vol. 577, Issue 1-2, pp. 111-6, (2004) (PubMed).

  • Target

    ISG20 (Interferon Stimulated Exonuclease Gene 20kDa (ISG20))

    Andere Bezeichnung

    ISG20

    Hintergrund

    ISG20 belongs to the the exonuclease superfamily. It is exonuclease with specificity for single-stranded RNA and, to a lesser extent for DNA. It degrades RNA at a rate that is approximately 35-fold higher than its rate for single-stranded DNA. It is involved in the antiviral function of IFN against RNA viruses.
    Alias Symbols: CD25, HEM45
    Protein Interaction Partner: UBC,
    Protein Size: 181

    Molekulargewicht

    20 kDa

    Gen-ID

    3669

    NCBI Accession

    NM_002201, NP_002192

    UniProt

    Q96AZ6
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