HNRNPK Antikörper (C-Term)

Produktnummer ABIN2778791

Dieses Anti-HNRNPK-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von HNRNPK in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio), Meerschweinchen, Ziege und Pferd.

Kurzübersicht für HNRNPK Antikörper (C-Term) (ABIN2778791)

Target: HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Zebrafisch (Danio rerio), Meerschweinchen, Ziege, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HNRNPK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HNRNPK Antikörper

Bindungsspezifität: C-Term

Sequenz: YSYAGGRGSY GDLGGPIITT QVTIPKDLAG SIIGKGGQRI KQIRHESGAS

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HNRPK. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HNRPK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 463 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HNRNPK

Target: HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))

Andere Bezeichnung: HNRPK

Hintergrund: HNRPK belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene is located in the nucleoplasm and has three repeats of KH domains that binds to RNAs. It is distinct among other hnRNP proteins in its binding preference, it binds tenaciously to poly(C). This protein is also thought to have a role during cell cycle progession. Multiple alternatively spliced transcript variants have been described for this gene but only three variants have been fully described.
Alias Symbols: CSBP, TUNP, HNRPK
Protein Interaction Partner: ZNF385C, ZFC3H1, RBMY1F, ZNF792, HNRNPLL, YTHDC1, PRR3, CCDC33, FBXL18, MARK4, PCDHB14, DALRD3, RASD1, RBMX, PRPF31, SORBS3, ABI2, HUWE1, MATR3, QKI, UBC, U2AF1, TYK2, TP53, SPG7, ZNRF2P1, C6orf226, RTP5, AQP5, GRB2, FUS, DOCK2, CIRBP, SNRPA, RBMY1A1, RBM
Protein Size: 463

Molekulargewicht: 51 kDa

Gen-ID: 3190

NCBI Accession: NM_031262, NP_112552

UniProt: P61978