FMR1 Antikörper (C-Term)

Produktnummer ABIN2778786

Der Kaninchen Polyklonal Anti-FMR1-Antikörper wurde für WB validiert. Er ist geeignet, FMR1 in Proben von Human, Maus, Ratte, Hund, Kaninchen, Schwein und Rind (Kuh) zu detektieren.

Kurzübersicht für FMR1 Antikörper (C-Term) (ABIN2778786)

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Schwein, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FMR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FMR1 Antikörper

Bindungsspezifität: C-Term

Sequenz: GGGFKGNDDH SRTDNRPRNP REAKGRTTDG SLQNTSSEGS RLRTGKDRNQ

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against FMR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of human FMR1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FMR1

Target: FMR1 (Fragile X Mental Retardation 1 (FMR1))

Andere Bezeichnung: FMR1

Hintergrund: The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
Alias Symbols: POF, FMRP, POF1, FRAXA
Protein Size: 262

Molekulargewicht: 28 kDa

Gen-ID: 2332

NCBI Accession: NM_001185075, NP_001172004

UniProt: Q06787

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development