DAZL Antikörper (C-Term)

Produktnummer ABIN2778769

Der Kaninchen Polyklonal Anti-DAZL-Antikörper wurde für WB validiert. Er ist geeignet, DAZL in Proben von Human, Maus, Ratte, Schaf, Rind (Kuh), Hund, Ziege, Meerschweinchen und Pferd zu detektieren.

Kurzübersicht für DAZL Antikörper (C-Term) (ABIN2778769)

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Reaktivität: Human, Maus, Ratte, Schaf, Rind (Kuh), Hund, Ziege, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DAZL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DAZL Antikörper

Bindungsspezifität: C-Term

Sequenz: EVDPGAEVVP NECSVHEATP PSGNGPQKKS VDRSIQTVVS CLFNPENRLR

Homologie: Cow: 93%, Dog: 93%, Goat: 93%, Guinea Pig: 86%, Horse: 92%, Human: 100%, Mouse: 93%, Rat: 86%, Sheep: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DAZL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DAZL

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 295 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DAZL

Target: DAZL (Deleted in Azoospermia-Like (DAZL))

Andere Bezeichnung: DAZL

Hintergrund: DAZ (Deleted in AZoospermia) is the potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. DAZL is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of the autosomal gene encoding DAZL during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in the Dazl gene have been linked to severe spermatogenic failure and infertility in males.The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DAZH, DAZL1, DAZLA, MGC26406, SPGYLA
Protein Interaction Partner: PUM2, DAZ1, UBC, DAZ4, DAZL, DAZAP2, DAZAP1,
Protein Size: 295

Molekulargewicht: 33 kDa

Gen-ID: 1618

NCBI Accession: NM_001351, NP_001342

UniProt: Q92904