RED1 Antikörper (N-Term)

Produktnummer ABIN2778757

Dieses Anti-RED1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RED1 in WB. Geeignet für Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Meerschweinchen und Kaninchen. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für RED1 Antikörper (N-Term) (ABIN2778757)

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Reaktivität: Human, Ratte, Maus, Zebrafisch (Danio rerio), Rind (Kuh), Hund, Pferd, Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RED1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RED1 Antikörper

Bindungsspezifität: N-Term

Sequenz: QLSNGGGGGP GRKRPLEEGS NGHSKYRLKK RRKTPGPVLP KNALMQLNEI

Homologie: Cow: 83%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against ADARB1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ADARB1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 701 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RED1 Antikörper (ABIN2778757)

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Details zu RED1

Target: RED1 (ADARB1) (Adenosine Deaminase, RNA-Specific, B1 (ADARB1))

Andere Bezeichnung: ADARB1

Hintergrund: ADARB1 is an enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site.This gene encodes the enzyme responsible for pre-mRNA editing of the glutamate receptor subunit B by site-specific deamination of adenosines. Studies in rat found that this enzyme acted on its own pre-mRNA molecules to convert an AA dinucleotide to an AI dinucleotide which resulted in a new splice site. Alternative splicing of this gene results in several transcript variants, some of which have been characterized by the presence or absence of an ALU cassette insert and a short or long C-terminal region.
Alias Symbols: RED1, ADAR2, DRABA2, DRADA2
Protein Interaction Partner: EBNA1BP2, IFRD2, CCDC124, NIFK, C7orf50, C1orf35, STRBP, BRIX1, SDAD1, ZFR, NOP16, MRTO4, RRS1, BMI1, APP, UBC, PPP2CB, WWP2, PIN1,
Protein Size: 701

Molekulargewicht: 77 kDa

Gen-ID: 104

NCBI Accession: NM_001112, NP_001103

UniProt: Q4AE79