CELF1 Antikörper (Middle Region)
Kurzübersicht für CELF1 Antikörper (Middle Region) (ABIN2778749)
Target
Alle CELF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- QMKPADSEKN NVEDRKLFIG MISKKCTEND IRVMFSSFGQ IEECRILRGP
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CUGBP1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human CUGBP1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 512 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CELF1 (CUGBP, Elav-Like Family Member 1 (CELF1))
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Andere Bezeichnung
- CUGBP1
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Hintergrund
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Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. This gene may play a role in myotonic dystrophy type 1 (DM1) via interactions with the dystrophia myotonica-protein kinase (DMPK) gene.
Alias Symbols: BRUNOL2, CUG-BP, CUGBP, CUGBP1, EDEN-BP, NAB50, NAPOR, hNab50
Protein Interaction Partner: UBC, MDM2, RPA3, RPA2, RPA1, BMI1, TARDBP, RALY, HNRNPC, APP, ELAVL1, SUMO2, USP10, FUBP1, PPBP, DMPK, TOM1L1, CELF1,
Protein Size: 512 -
Molekulargewicht
- 56 kDa
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Gen-ID
- 10658
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NCBI Accession
- NM_001172639, NP_001166110
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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