CARS Antikörper (Middle Region)

Produktnummer ABIN2778727

Dieses Anti-CARS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CARS in WB. Geeignet für Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für CARS Antikörper (Middle Region) (ABIN2778727)

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Pferd, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CARS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CARS Antikörper

Bindungsspezifität: Middle Region

Sequenz: QEQEAAKLAK MKIPPSEMFL SETDKYSKFD ENGLPTHDME GKELSKGQAK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 100%, Zebrafish: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against CARS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CARS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 831 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CARS

Target: CARS (Cysteinyl-tRNA Synthetase (CARS))

Andere Bezeichnung: CARS

Hintergrund: CARS is a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. CARS gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.This gene encodes a class 1 aminoacyl-tRNA synthetase, cysteinyl-tRNA synthetase. Each of the twenty aminoacyl-tRNA synthetases catalyzes the aminoacylation of a specific tRNA or tRNA isoaccepting family with the cognate amino acid. This gene is one of several located near the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Alias Symbols: CARS1, CYSRS, MGC:11246
Protein Interaction Partner: UBC, DNM1L, CAND1, LUC7L2, THUMPD3, JMJD6, XPO7, FAF1, SEC23A, SEC24D, HIRIP3, HIST1H4A, TTC1, TROVE2, SHMT1, PPM1G, PPAT, PAWR, KARS, IDE, HSPA4, GFPT1, GART, GARS, APEH, APP, SUMO2, PACSIN1, PACSIN3, PACSIN2, PSTPIP1, EEF1G,
Protein Size: 831

Molekulargewicht: 95 kDa

Gen-ID: 833

NCBI Accession: NM_001014437, NP_001014437

UniProt: Q5HYE4