EXOSC10 Antikörper (C-Term)

Produktnummer ABIN2778684

Dieses Anti-EXOSC10-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EXOSC10 in WB. Geeignet für Human, Maus, Rind (Kuh), Kaninchen, Ratte, Hund, Meerschweinchen, Pferd und Schwein. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für EXOSC10 Antikörper (C-Term) (ABIN2778684)

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Reaktivität: Human, Maus, Rind (Kuh), Kaninchen, Ratte, Hund, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOSC10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EXOSC10 Antikörper

Bindungsspezifität: C-Term

Sequenz: ACKAAAEQAI SVRQQVVLEN AAKKRERATS DPRTTEQKQE KKRLKISKKP

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against EXOSC10. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region region of human EXOSC10

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 885 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EXOSC10 Antikörper (ABIN2778684)

van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

Details zu EXOSC10

Target: EXOSC10 (Exosome Component 10 (EXOSC10))

Andere Bezeichnung: EXOSC10

Hintergrund: EXOSC10 contains 1 HRDC domain and 1 3'-5' exonuclease domain. Antibodies against PM/SCL are found in patients with polymyositis and/or scleroderma.
Alias Symbols: PM-Scl, PM/Scl-100, PMSCL, PMSCL2, RRP6, Rrp6p, p2, p3, p4
Protein Interaction Partner: SUMO2, UBC, SUMO1, RPA3, RPA2, RPA1, NOMO2, EXOSC6, FERMT3, CHPF, LSM2, EXOSC5, FOXRED1, EXOSC4, XRN1, LSM8, B9D1, USP21, UPF2, NOMO1, EXOSC7, DIS3, EXOSC8, IMMT, RUVBL2, EIF3M, TOX4, SSRP1, SKIV2L, LCAT, DXO, ALDH1B1, AICDA, ESR1, EXOSC3, EXOSC9, DIS3L,
Protein Size: 885

Molekulargewicht: 101 kDa

Gen-ID: 5394

NCBI Accession: NM_001001998, NP_001001998

UniProt: Q01780