RPLP0 Antikörper (N-Term)

Produktnummer ABIN2778681

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch RPLP0 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Kaninchen.Es wurde in 1 Publikation zitiert.

Kurzübersicht für RPLP0 Antikörper (N-Term) (ABIN2778681)

Target: RPLP0 (Ribosomal Protein, Large, P0 (RPLP0))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RPLP0 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RPLP0 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: RPLP0 Antibody - N-terminal region

Sequenz: TEIRDMLLAN KVPAAARAGA IAPCEVTVPA QNTGLGPEKT SFFQALGITT

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RPLP0. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPLP0

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8110748

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-RPLP0 Antikörper (ABIN2778681)

Luo, Zhong, Basu, Mayr: "mRNA 3'UTRs chaperone intrinsically disordered regions to control protein activity." in: bioRxiv : the preprint server for biology, (2025) (PubMed).

Details zu RPLP0

Target: RPLP0 (Ribosomal Protein, Large, P0 (RPLP0))

Andere Bezeichnung: RPLP0

Hintergrund:

Background Information: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. The ribosomal protein is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist, they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist, they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Gene Name: Ribosomal protein, large, P0

Alternative Symbols: P0, LP0, L10E, RPP0, PRLP0

Protein Name: 60S acidic ribosomal protein P0

Molekulargewicht: 34kDa

Gen-ID: 6175

NCBI Accession: NP_000993

UniProt: P05388