PHAP1 Antikörper (N-Term)

Produktnummer ABIN2778668

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHAP1 in WB und IHC. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schaf und Schwein.

Kurzübersicht für PHAP1 Antikörper (N-Term) (ABIN2778668)

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Kaninchen, Schaf, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-PHAP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: MEMGRRIHLE LRNRTPSDVK ELVLDNSRSN EGKLEGLTDE FEELEFLSTI

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 79%, Pig: 93%, Rabbit: 93%, Rat: 86%, Sheep: 77%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against ANP32A. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ANP32A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 249 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PHAP1

Target: PHAP1 (ANP32A) (Acidic (Leucine-Rich) Nuclear phosphoprotein 32 Family, Member A (ANP32A))

Andere Bezeichnung: ANP32A

Hintergrund: ANP32A is a novel potent heat-stable inhibitor protein of protein phosphatase 2A. It may play a key role in self-renewing cell populations where it may act in the nucleus to limit their sensitivity to transformation. Being a tumor suppressor, ANP32A represses cell growth through inhibition of transcription by blocking acetylation and phosphorylation of histone H3 and initiating its proapoptotic activity.
Alias Symbols: LANP, MAPM, PP32, HPPCn, PHAP1, PHAPI, I1PP2A, C15orf1
Protein Interaction Partner: UBC, rev, PDLIM5, PLIN3, ARPC1B, OXSR1, EIF4A3, VBP1, TPD52L2, SSB, SRP14, RPA2, PKM, BAG1, SOX2, PCBP1, ESR1, THRB, PPARG, PGR, KPNA6, KPNA5, KPNA1, SUMO2, CHAF1A, HIST1H4A, HIST1H3A, HIST2H2BE, HIST2H2AC, SET, MEPCE, ELAVL1, ADAP1, NSFL1C, HSPB3, AXIN1,
Protein Size: 249

Molekulargewicht: 29 kDa

Gen-ID: 8125

NCBI Accession: NM_006305, NP_006296

UniProt: P39687