PRMT2 Antikörper (Middle Region)

Produktnummer ABIN501938

Der Kaninchen Polyklonal Anti-PRMT2-Antikörper wurde für WB validiert. Er ist geeignet, PRMT2 in Proben von Human, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Hund und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für PRMT2 Antikörper (Middle Region) (ABIN501938)

Target: PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRMT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRMT2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VHTGDVVTGS VVLQRNPVWR RHMSVALSWA VTSRQDPTSQ KVGEKVFPIW

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PRMT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PRMT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 433 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PRMT2 Antikörper (ABIN501938)

Meyer, Wolf, Obendorf: "PRMT2, a member of the protein arginine methyltransferase family, is a coactivator of the androgen receptor." in: The Journal of steroid biochemistry and molecular biology, Vol. 107, Issue 1-2, pp. 1-14, (2007) (PubMed).

Details zu PRMT2

Target: PRMT2 (Protein Arginine Methyltransferase 2 (PRMT2))

Andere Bezeichnung: PRMT2

Hintergrund: The protein arginine methyltransferases (PRMTs) include a family of proteins with related putative methyltransferase domains that modify chromatin and regulate cellular transcription. PRMT2 inhibits NF-kappaB-dependent transcription and promotes apoptosis
Alias Symbols: HRMT1L1, MGC111373
Protein Interaction Partner: FIP1L1, SPAG8, RIPK2, BAG6, RB1, HNRNPA1, E2F1, UBC, PSMB3, HHV8GK18_gp81, CPSF7, DMRTB1, HNRNPUL1, PRMT2, THRB, PGR, NCOA6, NCOA1, ESR2, RXRA, PRRC2A, ESR1, PPARG, RARA,
Protein Size: 433

Molekulargewicht: 49 kDa

Gen-ID: 3275

NCBI Accession: NM_001535, NP_001526

UniProt: P55345

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding