SIRT5 Antikörper (Middle Region)

Produktnummer ABIN2778620

Der Kaninchen Polyklonal anti-SIRT5 Antikörper (ABIN2778620) detektiert spezifisch SIRT5 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Rind (Kuh), Ziege, Kaninchen und Schwein.

Kurzübersicht für SIRT5 Antikörper (Middle Region) (ABIN2778620)

Target: SIRT5 (Sirtuin 5 (SIRT5))

Reaktivität: Human, Maus, Rind (Kuh), Ziege, Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIRT5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SIRT5 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PICPALSGKG APEPGTQDAS IPVEKLPRCE EAGCGGLLRP HVVWFGENLD

Homologie: Cow: 79%, Goat: 79%, Human: 100%, Mouse: 79%, Pig: 86%, Rabbit: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against SIRT5. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIRT5

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 310 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIRT5

Target: SIRT5 (Sirtuin 5 (SIRT5))

Andere Bezeichnung: SIRT5

Hintergrund: SIRT5 is included in class III of the sirtuin family which ischaracterized by a sirtuin core domain. Human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class III of the sirtuin family. Alternative splicing of this gene results in two transcript variants.
Alias Symbols: SIR2L5
Protein Interaction Partner: SIRT3, UBC, HECW2, APP, RELA,
Protein Size: 310

Molekulargewicht: 34 kDa

Gen-ID: 23408

NCBI Accession: NM_012241, NP_036373

UniProt: Q9NXA8

Pathways: SARS-CoV-2 Protein Interaktom