RNF8 Antikörper (C-Term)

Produktnummer ABIN2778597

Der Kaninchen Polyklonal Anti-RNF8-Antikörper wurde für WB und IHC validiert. Er ist geeignet, RNF8 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund und Kaninchen zu detektieren.

Kurzübersicht für RNF8 Antikörper (C-Term) (ABIN2778597)

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Schwein, Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNF8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-RNF8 Antikörper

Bindungsspezifität: C-Term

Sequenz: MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE

Homologie: Cow: 100%, Dog: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RNF8. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human RNF8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 485 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNF8

Target: RNF8 (Ring Finger Protein 8 (RNF8))

Andere Bezeichnung: RNF8

Hintergrund: RNF8 contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins.The protein encoded by this gene contains a RING finger motif and a FHA domain. This protein has been shown to interact with several class II ubiquitin-conjugating enzymes (E2), including UBE2E1/UBCH6, UBE2E2, and UBE2E3, and may act as an ubiquitin ligase (E3) in the ubiquitination of certain nuclear proteins. Alternatively spliced transcript variants encoding distinct isoforms have been reported.
Alias Symbols: FLJ12013, KIAA0646
Protein Interaction Partner: TMEM79, HOMEZ, SEPT3, RBFOX2, PNMA2, USP16, WASL, HERC2, MAD1L1, VCP, TNFRSF1A, TNF, BCL10, UBE2N, UBC, NEDD8, JMJD1C, MDC1, EXOSC2, MDM2, BLM, SEPT8, SEPT7, RPSA, H2AFX, RL2, HIST2H2BE, HIST2H2AC, PCNA, RAD50, NBN, MRE11A, UBE2E3, UBE2V1, UBE2E2, UBE2E1,
Protein Size: 485

Molekulargewicht: 55 kDa

Gen-ID: 9025

NCBI Accession: NM_003958, NP_003949

UniProt: O76064

Pathways: Production of Molecular Mediator of Immune Response