MLX Antikörper (N-Term)

Produktnummer ABIN2778545

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch MLX in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Ziege, Pferd und Kaninchen und wurde in 1 Publikation erwähnt.

Kurzübersicht für MLX Antikörper (N-Term) (ABIN2778545)

Target: MLX (MAX-Like Protein X (MLX))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Ziege, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MLX Antikörper

Bindungsspezifität: N-Term

Sequenz: MTEPGASPED PWVKASPVGA HAGEGRAGRA RARRGAGRRG ASLLSPKSPT

Homologie: Cow: 100%, Dog: 93%, Goat: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MLX. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MLX

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 298 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MLX Antikörper (ABIN2778545)

Stoltzman, Peterson, Breen, Muoio, Billin, Ayer: "Glucose sensing by MondoA:Mlx complexes: a role for hexokinases and direct regulation of thioredoxin-interacting protein expression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 19, pp. 6912-7, (2008) (PubMed).

Details zu MLX

Target: MLX (MAX-Like Protein X (MLX))

Andere Bezeichnung: MLX

Hintergrund: MLX belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. MLX may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4.The product of this gene belongs to the family of basic helix-loop-helix leucine zipper (bHLH-Zip) transcription factors. These factors form heterodimers with Mad proteins and play a role in proliferation, determination and differentiation. This gene product may act to diversify Mad family function by its restricted association with a subset of the Mad family of transcriptional repressors, namely, Mad1 and Mad4. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Alias Symbols: MAD7, MXD7, TCFL4, bHLHd13
Protein Interaction Partner: ZBTB32, GABARAPL2, RBM39, AES, UBC, SAP30BP, ID3, APP, SUMO1, MLXIPL, MLXIP, MXD4, MNT, MAD1L1, MLX, MXD1,
Protein Size: 298

Molekulargewicht: 33 kDa

Gen-ID: 6945

NCBI Accession: NM_170607, NP_733752

UniProt: Q9UH92