ZNF384 Antikörper (C-Term)

Produktnummer ABIN2778449

Dieses Anti-ZNF384-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von ZNF384 in WB. Geeignet für Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen und Maus.

Kurzübersicht für ZNF384 Antikörper (C-Term) (ABIN2778449)

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Reaktivität: Human, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF384 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZNF384 Antikörper

Bindungsspezifität: C-Term

Sequenz: QQPPPHFQSP GAAPQGGGGG DSNPNPPPQC SFDLTPYKTA EHHKDICLTV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF384. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 461 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF384

Target: ZNF384 (Zinc Finger Protein 384 (ZNF384))

Andere Bezeichnung: ZNF384

Hintergrund: This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7.
Alias Symbols: CAGH1, CAGH1A, CIZ, ERDA2, FLJ59043, NMP4, NP, TNRC1
Protein Interaction Partner: SOX2, UBC, OPTN, tat, HOXC9, CEBPE, TAF15, ZYX, PCBP1, VIM,
Protein Size: 461

Molekulargewicht: 50 kDa

Gen-ID: 171017

NCBI Accession: NM_001039920, NP_001035009