ZNF496 Antikörper (N-Term)

Produktnummer ABIN2778404

Der Kaninchen Polyklonal anti-ZNF496 Antikörper (ABIN2778404) detektiert spezifisch ZNF496 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Rind (Kuh), Ratte, Schaf, Hund, Pferd, Schwein, Kaninchen und Meerschweinchen.

Kurzübersicht für ZNF496 Antikörper (N-Term) (ABIN2778404)

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Reaktivität: Human, Maus, Rind (Kuh), Ratte, Schaf, Hund, Pferd, Schwein, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZNF496 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ZNF496 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ZNF496 Antibody - N-terminal region

Sequenz: MPTALCPRVL APKESEEPRK MRSPPGENPS PQGELPSPES SRRLFRRFRY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ZNF496. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZNF496

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8116682

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ZNF496

Target: ZNF496 (Zinc Finger Protein 496 (ZNF496))

Andere Bezeichnung: ZNF496

Hintergrund:

Background Information: ZNF496 contains a SCAN box, a KRAB-A domain, and four consensus C2H2-type zinc fingers preceded by a unique finger derivative, referred to herein as the C2HR motif. The C2HR motif functions to mediate protein-protein interaction with the cysteine-rich (C5HCH) domain of NSD1 in a Zn(II)-dependent fashion, and when tethered to RNA polymerase II promoters, represses transcription in an NSD1-dependent manner. ZNF496 contains a novel type of zinc finger motif that functions as a docking site for NSD1 and is more than just a degenerate evolutionary remnant of a C2H2 motif.

Gene Name: Zinc finger protein 496

Alternative Symbols: NIZP1, ZFP496, ZSCAN49, ZKSCAN17

Protein Name: Zinc finger protein 496

Molekulargewicht: 67kDa

Gen-ID: 84838

NCBI Accession: NP_116141

UniProt: Q96IT1