AFF3 Antikörper (Middle Region)

Produktnummer ABIN2778345

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch AFF3 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Schwein, Kaninchen, Ratte und Hund und wurde in 1 Publikation erwähnt.

Kurzübersicht für AFF3 Antikörper (Middle Region) (ABIN2778345)

Target: AFF3 (AF4/FMR2 Family, Member 3 (AFF3))

Reaktivität: Human, Maus, Schwein, Kaninchen, Ratte, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AFF3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AFF3 Antikörper

Bindungsspezifität: Middle Region

Sequenz: APATKDSESA PPSHTSDTPA EKALPKSKRK RKCDNEDDYR EIKKSQGEKD

Homologie: Dog: 86%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 77%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against AFF3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human AFF3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1226 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-AFF3 Antikörper (ABIN2778345)

To, Faseruk, Gokgoz, Pinnaduwage, Done, Andrulis: "LAF-4 is aberrantly expressed in human breast cancer." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 4, pp. 568-74, (2005) (PubMed).

Details zu AFF3

Target: AFF3 (AF4/FMR2 Family, Member 3 (AFF3))

Andere Bezeichnung: AFF3

Hintergrund: AFF3 is a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL.This gene encodes a tissue-restricted nuclear transcriptional activator that is preferentially expressed in lymphoid tissue. Isolation of this protein initially defined a highly conserved LAF4/MLLT2 gene family of nuclear transcription factors that may function in lymphoid development and oncogenesis. In some ALL patients, this gene has been found fused to the gene for MLL. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: LAF4, MLLT2-like
Protein Interaction Partner: CDK9, MLLT3,
Protein Size: 1226

Molekulargewicht: 133 kDa

Gen-ID: 3899

NCBI Accession: NM_002285, NP_002276

UniProt: P51826