Afadin Antikörper (N-Term)
Kurzübersicht für Afadin Antikörper (N-Term) (ABIN2778340)
Target
Alle Afadin (MLLT4) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- GVIQNFKRTL SKKEKKEKKK REKEALRQAS DKDDRPFQGE DVENSRLAAE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 85%, Rat: 100%, Yeast: 92%, Zebrafish: 91%
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Produktmerkmale
- This is a rabbit polyclonal antibody against MLLT4. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human MLLT4
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 674 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Afadin (MLLT4)
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Andere Bezeichnung
- MLLT4
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Hintergrund
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AF6 is a Ras target that regulates cell-cell adhesions downstream of Ras activation. It is fused with MLL in leukemias caused by t(6,11) translocations.
Alias Symbols: RP3-470B24.4, AF-6, AF6, AFADIN, FLJ34371, RP3-431P23.3
Protein Interaction Partner: UBC, LGR4, LATS2, YWHAQ, YWHAE, VCAM1, SMAD2, ITGA4, GRB2, FN1, SIRT7, HNRNPA1, ARRB2, YWHAG, YWHAB, KMT2A, MEN1, PVRL4, PICK1, RIT2, SORBS2, F11R, NRXN2, SSX2IP, RIT1, NRXN3, PVRL3, PVRL1, MRAS, SORBS1, EPHB6, EPHA7, JAG1, EPHB3, RALGDS, TJP1, EPHB2, PVR
Protein Size: 674 -
Molekulargewicht
- 74 kDa
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Gen-ID
- 4301
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NCBI Accession
- NM_001040000
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UniProt
- P55196
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Pathways
- Cell-Cell Junction Organization
Target
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