PAX8 Antikörper (C-Term)

Produktnummer ABIN2778308

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAX8 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen und Schwein.

Kurzübersicht für PAX8 Antikörper (C-Term) (ABIN2778308)

Target: PAX8 (Paired Box 8 (PAX8))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAX8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAX8 Antikörper

Bindungsspezifität: C-Term

Sequenz: TPSNTPLGRN LSTHQTYPVV ADPHSPFAIK QETPEVSSSS STPSSLSSSA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PAX8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PAX8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAX8

Target: PAX8 (Paired Box 8 (PAX8))

Andere Bezeichnung: PAX8

Hintergrund: PAX8 is a member of the paired box (PAX) family of transcription factors. Members of this family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in its gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
Alias Symbols: -
Protein Interaction Partner: SERINC1, ANXA7, PKM, CXCL9, CHUK, POU2AF1, WBP2, SMAD3, EP300, NKX2-1, ID2,
Protein Size: 450

Molekulargewicht: 48 kDa

Gen-ID: 7849

NCBI Accession: NM_013992, NP_054698

UniProt: Q06710

Pathways: Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation