SUPT5H Antikörper (Middle Region)

Produktnummer ABIN2778245

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-SUPT5H Antikörper wird verwendet zum Nachweis von SUPT5H in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen und Zebrafisch (Danio rerio). Er wurde validiert für WB.

Kurzübersicht für SUPT5H Antikörper (Middle Region) (ABIN2778245)

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUPT5H Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SUPT5H Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: SUPT5H Antibody - middle region

Sequenz: FEDQPEGIDL EVVTESTGKE REHNFQPGDN VEVCEGELIN LQGKILSVDG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against SUPT5H. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SUPT5H

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34064-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-SUPT5H Antikörper (ABIN2778245)

Ueki, Lin, Senoo, Ebihara, Agata, Onji, Saheki, Kawai, Mukherjee, Reichenberger, Olsen: "Increased myeloid cell responses to M-CSF and RANKL cause bone loss and inflammation in SH3BP2 "cherubism" mice." in: Cell, Vol. 128, Issue 1, pp. 71-83, (2007) (PubMed).

Amir-Zilberstein, Ainbinder, Toube, Yamaguchi, Handa, Dikstein: "Differential regulation of NF-kappaB by elongation factors is determined by core promoter type." in: Molecular and cellular biology, Vol. 27, Issue 14, pp. 5246-59, (2007) (PubMed).

Details zu SUPT5H

Target: SUPT5H (Transcription Elongation Factor SPT5 (SUPT5H))

Andere Bezeichnung: SUPT5H

Hintergrund:

Background Information: SUPT5H and its binding partner regulate transcriptional elongation by RNA polymerase II. SPT4 and SPT5 are involved in both 5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB)-mediated transcriptional inhibition and the activation of transcriptional elongation by the human immunodeficiency virus type 1 (HIV-1) Tat protein.

Gene Name: Suppressor of Ty 5 homolog (S. cerevisiae)

Alternative Symbols: SPT5, SPT5H, Tat-CT1

Protein Name: Transcription elongation factor SPT5

Molekulargewicht: 121kDa

Gen-ID: 6829

NCBI Accession: NP_003160

UniProt: O00267