RGS20 Antikörper (N-Term)
Quick Overview for RGS20 Antikörper (N-Term) (ABIN2778241)
Target
Alle RGS20 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- NACCFCWCCC CSCSCLTVRN QEDQRPTIAS HELRADLPTW EESPAPTLEE
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Spezifität
- 100 % homologous to isoforms 1, 2, 4-6.
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Homologie
- Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 85%, Rat: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against RGS20. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 241 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RGS20 (Regulator of G-Protein Signaling 20 (RGS20))
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Andere Bezeichnung
- RGS20
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Hintergrund
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The protein encoded by this gene belongs to the family of regulator of G protein signaling (RGS) proteins, which are regulatory and structural components of G protein-coupled receptor complexes. RGS proteins inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound forms. This protein selectively binds to G(z)-alpha and G(alpha)-i2 subunits, and regulates their signaling activities. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: RGSZ1, ZGAP1
Protein Interaction Partner: KRTAP5-6, LCE3E, LCE2D, LCE2A, LCE1B, KLHL38, LCE4A, TBC1D16, CATSPER1, PTPMT1, KRTAP4-2, CRCT1, PVRL3, MAPKBP1, GLRX3, CREB5, PTGER3, OTX1, KRTAP5-9, INS, HSPD1, HOXA1, GNAI2, AQP1, FASLG, KIF1A, ADRB2, OSTM1, STMN2, GNAI3, GNAI1, GNAZ, UBC, GNAO1, TXLNA
Protein Size: 241 -
Molekulargewicht
- 27 kDa
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Gen-ID
- 8601
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NCBI Accession
- NM_003702, NP_003693
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UniProt
- O76081
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Pathways
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
Target
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