RGS13 Antikörper (Middle Region)

Produktnummer ABIN2778239

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch RGS13 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Pferd und Kaninchen.

Kurzübersicht für RGS13 Antikörper (Middle Region) (ABIN2778239)

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RGS13 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-RGS13 Antikörper

Bindungsspezifität: Middle Region

Sequenz: WSRISRAKKL YKIYIQPQSP REINIDSSTR ETIIRNIQEP TETCFEEAQK

Homologie: Cow: 100%, Dog: 100%, Horse: 92%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against RGS13. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human RGS13

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 159 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RGS13

Target: RGS13 (Regulator of G-Protein Signaling 13 (RGS13))

Andere Bezeichnung: RGS13

Hintergrund: The protein encoded by RGS13 is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown.
Protein Interaction Partner: GNAI2, GNA11, UBC, PRKACA, CREB1, GNAQ,
Protein Size: 159

Molekulargewicht: 17 kDa

Gen-ID: 6003

NCBI Accession: NM_144766, NP_658912

UniProt: O14921

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling