BRD4 Antikörper (N-Term)

Produktnummer ABIN2778228

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch BRD4 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd und Zebrafisch (Danio rerio).

Kurzübersicht für BRD4 Antikörper (N-Term) (ABIN2778228)

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BRD4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BRD4 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: BRD4 Antibody - N-terminal region

Sequenz: NPPPPEYINT KKNGRLTNQL QYLQKVVLKD LWKHSFSWPF QRPVDAVKLQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against BRDT. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human BRD4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34016-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu BRD4

Target: BRD4 (Bromodomain Containing 4 (BRD4))

Andere Bezeichnung: BRD4

Hintergrund:

Background Information: The protein encoded by this gene is homologous to the murine protein MCAP, which associates with chromosomes during mitosis, and to the human RING3 protein, a serine/threonine kinase. Each of these proteins contains two bromodomains, a conserved sequence motif which may be involved in chromatin targeting. This gene has been implicated as the chromosome 19 target of translocation t(15,19)(q13,p13.1), which defines an upper respiratory tract carcinoma in young people. Two alternatively spliced transcript variants have been described.

Gene Name: bromodomain containing 4

Alternative Symbols: CAP, MCAP, HUNK1, HUNKI

Protein Name: bromodomain-containing protein 4

Molekulargewicht: 50kDa

Gen-ID: 23476

NCBI Accession: NP_055114

UniProt: O60885

Pathways: Chromatin Binding, SARS-CoV-2 Protein Interaktom