ACADL Antikörper (Middle Region)

Produktnummer ABIN2778159

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-ACADL Antikörper wird verwendet zum Nachweis von ACADL in Proben von Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio) und Meerschweinchen. Er wurde validiert für WB.

Kurzübersicht für ACADL Antikörper (Middle Region) (ABIN2778159)

Target: ACADL (Acyl-CoA Dehydrogenase, Long Chain (ACADL))

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Kaninchen, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACADL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ACADL Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: ACADL Antibody - middle region

Sequenz: LPQERLLIAD VAISASEFMF EETRNYVKQR KAFGKTVAHL QTVQHKLAEL

Homologie: Cow: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 77%

Produktmerkmale: This is a rabbit polyclonal antibody against ACADL. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ACADL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093964

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-ACADL Antikörper (ABIN2778159)

Mells, Fu, Sharma, Olson, Cheng, Handy, Saxena, Sorescu, Anania: "Glp-1 analog, liraglutide, ameliorates hepatic steatosis and cardiac hypertrophy in C57BL/6J mice fed a Western diet." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 302, Issue 2, pp. G225-35, (2012) (PubMed).

Details zu ACADL

Target: ACADL (Acyl-CoA Dehydrogenase, Long Chain (ACADL))

Andere Bezeichnung: ACADL

Hintergrund:

Background Information: ACADL belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family, which is a family of mitochondrial flavoenzymes involved in fatty acid and branched chain amino-acid metabolism. This protein is one of the four enzymes that catalyze the initial step of mitochondrial beta-oxidation of straight-chain fatty acid. Defects in this gene are the cause of long-chain acyl-CoA dehydrogenase (LCAD) deficiency, leading to nonketotic hypoglycemia.

Gene Name: Acyl-CoA dehydrogenase, long chain

Alternative Symbols: LCAD, ACAD4

Protein Name: Long-chain specific acyl-CoA dehydrogenase, mitochondrial

Molekulargewicht: 44kDa

Gen-ID: 33

NCBI Accession: NP_001599

UniProt: P28330

Pathways: Monocarboxylic Acid Catabolic Process