Asialoglycoprotein Receptor 1 Antikörper (N-Term)
Kurzübersicht für Asialoglycoprotein Receptor 1 Antikörper (N-Term) (ABIN2778132)
Target
Alle Asialoglycoprotein Receptor 1 (ASGR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- RKMKSLESQL EKQQKDLSED HSSLLLHVKQ FVSDLRSLSC QMAALQGNGS
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Homologie
- Cow: 85%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rat: 92%, Yeast: 75%
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Produktmerkmale
- This is a rabbit polyclonal antibody against ASGR1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human ASGR1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 291 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Asialoglycoprotein Receptor 1 (ASGR1)
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Andere Bezeichnung
- ASGR1
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Hintergrund
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ASGR1 encodes for a cell surface receptor binds to galactose-terminated glycoproteins. It transports these glycoproteins via a series of membrane vesicles and tubules to an acidic-sorting organelle where the receptor and ligand dissociates. Then the receptor is recycled back to the cell surface.
Alias Symbols: HL-1, ASGPR, ASGPR1, CLEC4H1
Protein Interaction Partner: CERS2, HIVEP1, SYVN1, VKORC1, FBXO6, EDEM1, HSPA5, CANX, APP, CLEC4G, NLK, RBBP6, HSP90B1, TG, HSP90AA1, DHFR, ASGR2, ITGA1,
Protein Size: 291 -
Molekulargewicht
- 33 kDa
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Gen-ID
- 432
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NCBI Accession
- NM_001671, NP_001662
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UniProt
- Q6FGQ5
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Pathways
- Thyroid Hormone Synthesis
Target
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