TNKS Antikörper (Middle Region)

Produktnummer ABIN2778109

Produktdetails anti-TNKS Antikörper

Target: TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Pferd, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNKS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: VSASLISPAS TPSCLSAASS IDNLTGPLAE LAVGGASNAG DGAAGTERKE

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TNKS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNKS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1327 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNKS

Target: TNKS (Tankyrase, TRF1-Interacting Ankyrin-Related ADP-Ribose Polymerase (TNKS))

Andere Bezeichnung: TNKS (TNKS Produkte)

Synonyme: wu:fe02c12 antikoerper, ARTD5 antikoerper, PARP-5a antikoerper, PARP5A antikoerper, PARPL antikoerper, TIN1 antikoerper, TINF1 antikoerper, TNKS1 antikoerper, pART5 antikoerper, 4930554K12Rik antikoerper, AI662855 antikoerper, C86528 antikoerper, D130072O21Rik antikoerper, TANK1 antikoerper, mTNKS1 antikoerper, tankyrase-1 antikoerper, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase b antikoerper, tankyrase antikoerper, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase antikoerper, tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 S homeolog antikoerper, tnksb antikoerper, TNKS antikoerper, Tnks antikoerper, tnks2.S antikoerper

Hintergrund: TNKS may regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4/GLUT4-vesicles. It has PARP activity and can modify TERF1, and thereby contribute to the regulation of telomere length.
Alias Symbols: PARP-5a, PARP5A, PARPL, TIN1, TINF1, TNKS1, pART5
Protein Interaction Partner: RNF146, RAPGEF2, TINF2, TNKS, TERF1, SH3BP2, APC, BLZF1, GMDS, UBC, DISC1, TNIK, SH3BP5, TERF2, FANCD2, BABAM1, VPS33A, FNBP1, MCL1, POT1, TNKS2, TNKS1BP1, NUMA1, LNPEP,
Protein Size: 1327

Molekulargewicht: 142 kDa

Gen-ID: 8658

NCBI Accession: NM_003747, NP_003738

UniProt: O95271