HAND1 Antikörper (N-Term)

Produktnummer ABIN2778103

Produktdetails anti-HAND1 Antikörper

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Schaf, Rind (Kuh), Meerschweinchen, Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAND1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CHQERPYFQS WLLSPADAAP DFPAGGPPPA AAAAATAYGP DARPGQSPGR

Homologie: Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 92%, Human: 100%, Mouse: 100%, Rabbit: 85%, Rat: 100%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against HAND1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HAND1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 215 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HAND1

Target: HAND1 (Heart and Neural Crest Derivatives Expressed 1 (HAND1))

Andere Bezeichnung: HAND1 (HAND1 Produkte)

Synonyme: CATG antikoerper, CG antikoerper, Hxt antikoerper, Thing1 antikoerper, bHLHa27 antikoerper, eHand antikoerper, eHAND antikoerper, hand-1 antikoerper, hand1-A antikoerper, HXT antikoerper, HAND1 antikoerper, hxt antikoerper, thing1 antikoerper, EHAND antikoerper, Hand1 antikoerper, Ehand1 antikoerper, Th1 antikoerper, cathepsin G antikoerper, heart and neural crest derivatives expressed 1 antikoerper, heart and neural crest derivatives expressed 1 L homeolog antikoerper, CTSG antikoerper, HAND1 antikoerper, Hand1 antikoerper, hand1.L antikoerper, hand1 antikoerper

Hintergrund: The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, it has been suggested that this transcription factor may be required for early trophoblast differentiation.
Alias Symbols: Hxt, eHand, Thing1, bHLHa27, HAND1
Protein Interaction Partner: SRA1, HEYL, PPP2R5D, HEY2, FHL2, HAND2, HAND1, PRKACA, TCF12, PRKCA, MYOD1, TCF3, ACHE,
Protein Size: 215

Molekulargewicht: 23 kDa

Gen-ID: 9421

NCBI Accession: NM_004821, NP_004812

UniProt: O96004

Pathways: Tube Formation