CLOCK Antikörper (N-Term)

Produktnummer ABIN2778091

Der Kaninchen Polyklonal Anti-CLOCK-Antikörper wurde für WB validiert. Er ist geeignet, CLOCK in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Kaninchen und Zebrafisch (Danio rerio) zu detektieren.

Kurzübersicht für CLOCK Antikörper (N-Term) (ABIN2778091)

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schaf, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLOCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CLOCK Antikörper

Bindungsspezifität: N-Term

Sequenz: LFTVSCSKMS SIVDRDDSSI FDGLVEEDDK DKAKRVSRNK SEKKRRDQFN

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CLOCK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CLOCK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 846 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CLOCK

Target: CLOCK (Clock Homolog (Mouse) (CLOCK))

Andere Bezeichnung: CLOCK

Hintergrund: CLOCK is a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1.This gene encodes a protein that belongs to the basic helix-loop-helix (bHLH) family of transcription factors. Polymorphisms within the encoded protein have been associated with circadian rhythm sleep disorders. A similar protein in mice is a circadian regulator that acts as a transcription factor and forms a heterodimer with aryl hydrocarbon receptor nuclear translocator-like to activate transcription of mouse period 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: KAT13D, KIAA0334, bHLHe8
Protein Interaction Partner: SIRT1, ARNTL, SOX2, TFAP4, UBC, ARNTL2, PER3, RXRA, RARA, KAT2B, EP300,
Protein Size: 846

Molekulargewicht: 95 kDa

Gen-ID: 9575

NCBI Accession: NM_004898, NP_004889

UniProt: O15516

Pathways: Regulation of Lipid Metabolism by PPARalpha, Photoperiodism