DKFZp686M216 (N-Term) Antikörper

Produktnummer ABIN2778072

Der Kaninchen Polyklonal anti-DKFZp686M216 Antikörper (ABIN2778072) detektiert spezifisch DKFZp686M216 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte, Schaf und Zebrafisch (Danio rerio).

Kurzübersicht für DKFZp686M216 (N-Term) Antikörper (ABIN2778072)

Target: DKFZp686M216

Reaktivität: Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte, Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Applikation: Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Sequenz: VTLPVAPMAA TGQVRMAGAM PARGGKRRSG MDFDDEDGEG PSKFSRENHS

Spezifität: This antibody is specific to both isoforms of hARNT2.

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DKFZp686M216. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human DKFZp686M216

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: DKFZp686M216

Hintergrund: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting addition roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
Alias Symbols: bHLHe1, DKFZp686M216
Protein Interaction Partner: TRIM42, CEP57L1, RFX6, MIPOL1, DYDC1, SSX2IP, DTX2, SYCE1, RIMBP3, ZNF341, LZTS2, USHBP1, CEP63, CCDC33, NPAS3, RINT1, NDE1, ADAMTSL4, MTUS2, IKZF3, RBCK1, SPAG5, TACC3, CALCOCO2, SORBS3, PDE4DIP, TRAF4, BZRAP1, TFIP11, SSBP3, DGCR6, NCOA3, TRIP6, TRAF2,
Protein Size: 717

Molekulargewicht: 79 kDa

Gen-ID: 9915

UniProt: Q9HBZ2