Pirin Antikörper (C-Term)
Kurzübersicht für Pirin Antikörper (C-Term) (ABIN2778063)
Target
Alle Pirin (PIR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Sequenz
- EPHHTAVLGE GDSVQVENKD PKRSHFVLIA GEPLREPVIQ HGPFVMNTNE
-
Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 93%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 79%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against PIR. It was validated on Western Blot using a cell lysate as a positive control.
-
Aufreinigung
- Protein A purified
-
Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human PIR
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 290 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- Pirin (PIR)
-
Andere Bezeichnung
- PIR
-
Hintergrund
-
PIR is a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.This gene encodes a member of the cupin superfamily. The encoded protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor as well as B cell lymphoma 3-encoded oncoprotein suggest the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication. Alternatively spliced transcript variants have been described.
Protein Interaction Partner: SMAD9, UBL7, SPEN, SUGT1, STAM, PSMB2, PPP2CA, CLNS1A, ARHGDIA, NFIX, NFKBIA, BCL3,
Protein Size: 290 -
Molekulargewicht
- 32 kDa
-
Gen-ID
- 8544
-
NCBI Accession
- NM_003662, NP_003653
-
UniProt
- O00625
Target
-