Claudin 1 Antikörper (C-Term)

Produktnummer ABIN2778045

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-Claudin 1 Antikörper (ABIN2778045) detektiert spezifisch Claudin 1 in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für Claudin 1 Antikörper (C-Term) (ABIN2778045)

Target: Claudin 1 (CLDN1)

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Schaf, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Claudin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Claudin 1 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: CLDN1 Antibody - C-terminal region

Sequenz: GQALFTGWAA ASLCLLGGAL LCCSCPRKTT SYPTPRPYPK PAPSSGKDYV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%, Sheep: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CLDN1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33623-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-Claudin 1 Antikörper (ABIN2778045)

Coyne, Gambling, Boucher, Carson, Johnson: "Role of claudin interactions in airway tight junctional permeability." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 285, Issue 5, pp. L1166-78, (2003) (PubMed).

Details zu Claudin 1

Target: Claudin 1 (CLDN1)

Andere Bezeichnung: CLDN1

Hintergrund:

Background Information: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. This protein, a member of the claudin family, is an integral membrane protein and a component of tight junction strands.

Gene Name: Claudin 1

Alternative Symbols: CLD1, SEMP1, ILVASC

Protein Name: Claudin-1

Molekulargewicht: 23 kDa

Gen-ID: 9076

NCBI Accession: NP_066924

UniProt: O95832

Pathways: Cell-Cell Junction Organization, Hepatitis C