Claudin 9 Antikörper (C-Term)
Kurzübersicht für Claudin 9 Antikörper (C-Term) (ABIN2778042)
Target
Alle Claudin 9 (CLDN9) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- WAAAALLMLG GGLLCCTCPP PQVERPRGPR LGYSIPSRSG ASGLDKRDYV
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CLDN9. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human CLDN9
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 217 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression." in: American journal of physiology. Cell physiology, Vol. 297, Issue 3, pp. C775-87, (2009) (PubMed).
: "Claudins 6, 9, and 13 are developmentally expressed renal tight junction proteins." in: American journal of physiology. Renal physiology, Vol. 291, Issue 6, pp. F1132-41, (2006) (PubMed).
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: "Inhibition of basal p38 or JNK activity enhances epithelial barrier function through differential modulation of claudin expression." in: American journal of physiology. Cell physiology, Vol. 297, Issue 3, pp. C775-87, (2009) (PubMed).
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- Claudin 9 (CLDN9)
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Andere Bezeichnung
- CLDN9
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Hintergrund
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CLDN9 is a member of claudin family. It is a four-transmembrane protein with WWCC motif, defined by W-X(17-22)-W-X(2)-C-X(8-10)-C.
Protein Size: 217 -
Molekulargewicht
- 24 kDa
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Gen-ID
- 9080
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NCBI Accession
- NM_020982, NP_066192
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UniProt
- O95484
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Pathways
- Cell-Cell Junction Organization, Hepatitis C
Target
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