Claudin 7 Antikörper (Middle Region)
Kurzübersicht für Claudin 7 Antikörper (Middle Region) (ABIN2778038)
Target
Alle Claudin 7 (CLDN7) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- GPAIFIGWAG SALVILGGAL LSCSCPGNES KAGYRVPRSY PKSNSSKEYV
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Homologie
- Cow: 79%, Dog: 79%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 86%, Rat: 93%, Sheep: 79%, Yeast: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against CLDN7. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human CLDN7
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 211 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Claudin 7 (CLDN7)
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Andere Bezeichnung
- CLDN7
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Hintergrund
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Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells.Claudins, such as CLDN7, are involved in the formation of tight junctions between epithelial cells. Tight junctions restrict lateral diffusion of lipids and membrane proteins, and thereby physically define the border between the apical and basolateral compartments of epithelial cells (Zheng et al., 2003 [PubMed 14502431]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CEPTRL2, CPETRL2, Hs.84359, claudin-1, CLDN-7
Protein Interaction Partner: SYNE4, HGD, LNX1, UBC, TJP1, RHOXF2, EPCAM,
Protein Size: 211 -
Molekulargewicht
- 22 kDa
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Gen-ID
- 1366
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NCBI Accession
- NM_001307, NP_001298
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UniProt
- O95471
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Pathways
- Hepatitis C
Target
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