PIK3R3 Antikörper (Middle Region)
Kurzübersicht für PIK3R3 Antikörper (Middle Region) (ABIN2777993)
Target
Alle PIK3R3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- EYTRTSQEIQ MKRTAIEAFN ETIKIFEEQC HTQEQHSKEY IERFRREGNE
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PIK3R3. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PIK3R3
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 461 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PIK3R3 (Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3))
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Andere Bezeichnung
- PIK3R3
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Hintergrund
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PIK3R3 binds to activated (phosphorylated) protein-tyrosine kinases through its SH2 domain and regulates their kinase activity. During insulin stimulation, it also binds to IRS-1.
Alias Symbols: DKFZp686P05226, FLJ41892, p55-GAMMA, p55
Protein Interaction Partner: FSD2, L3MBTL3, TRIM54, IRS4, LYN, MBIP, KHDRBS1, GRB2, ERBB3, ERBB2, EGFR, PIK3R2, CRK, RING1, QARS, PSME1, ORM1, KARS, GC, FGB, DARS, AMBP, VBP1, FBN3, DSN1, KLC2, MICAL1, KIAA1377, LUC7L2, TRMT2A, ABCB6, SERF1A, DRAP1, IRS2, TEC, RB1, PDGFRB, PIK3CA, IN
Protein Size: 461 -
Molekulargewicht
- 54 kDa
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Gen-ID
- 8503
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NCBI Accession
- NM_003629, NP_003620
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UniProt
- Q92569
Target
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