WHSC1 Antikörper (N-Term)

Produktnummer ABIN182817

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-WHSC1 Antikörper (ABIN182817) detektiert spezifisch WHSC1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für WHSC1 Antikörper (N-Term) (ABIN182817)

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WHSC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-WHSC1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NSD2 Antibody - N-terminal region

Sequenz: KYNVGDLVWS KVSGYPWWPC MVSADPLLHS YTKLKGQKKS ARQYHVQFFG

Homologie: Dog: 93%, Guinea Pig: 88%, Horse: 100%, Human: 100%, Mouse: 86%, Rabbit: 76%, Rat: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against WHSC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human WHSC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8115936

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-WHSC1 Antikörper (ABIN182817)

Li, Yin, Okamoto, Mushlin, Balgley, Lee, Yuan, Ikejiri, Glasker, Vortmeyer, Oldfield, Weil, Zhuang: "Identification of a novel proliferation-related protein, WHSC1 4a, in human gliomas." in: Neuro-oncology, Vol. 10, Issue 1, pp. 45-51, (2008) (PubMed).

Details zu WHSC1

Target: WHSC1 (Wolf-Hirschhorn Syndrome Candidate 1 (WHSC1))

Andere Bezeichnung: NSD2

Hintergrund:

Background Information: This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4,14)(p16.3,q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences.

Gene Name: nuclear receptor binding SET domain protein 2

Alternative Symbols: WHS, TRX5, KMT3F, KMT3G, MMSET, WHSC1, REIIBP

Protein Name: histone-lysine N-methyltransferase NSD2

Molekulargewicht: 88kDa

Gen-ID: 7468

NCBI Accession: NP_055734

UniProt: O96031

Pathways: SARS-CoV-2 Protein Interaktom