Tumor Protein p73 Antikörper (Middle Region)
Kurzübersicht für Tumor Protein p73 Antikörper (Middle Region) (ABIN2777953)
Target
Alle Tumor Protein p73 (TP73) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
 - Middle Region
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Sequenz
 - RRSFEGRICA CPGRDRKADE DHYREQQALN ESSAKNGAAS KRAFKQSPPA
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Homologie
 - Cow: 100%, Dog: 92%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%
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Produktmerkmale
 - This is a rabbit polyclonal antibody against TP73. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
 - Affinity Purified
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Immunogen
 - The immunogen is a synthetic peptide directed towards the middle region of human TP73
 
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Applikationshinweise
 - Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 636 AA
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Beschränkungen
 - Nur für Forschungszwecke einsetzbar
 
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Format
 - Liquid
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Konzentration
 - Lot specific
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Buffer
 - Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
 - Sodium azide
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Vorsichtsmaßnahmen
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
 - Avoid repeated freeze-thaw cycles.
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Lagerung
 - -20 °C
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Informationen zur Lagerung
 - For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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- Tumor Protein p73 (TP73) (Tumor Protein P73 (TP73))
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Andere Bezeichnung
 - TP73
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Hintergrund
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                        TP73 belongs to the p53 family. It participates in the apoptotic response to DNA damage. When overproduced, it activates transcription from p53-responsive promoters and induces apoptosis. TP53 may be a tumor suppressor protein. 
Alias Symbols: P73
Protein Interaction Partner: FUS, YAP1, WWOX, UBC, TRIM32, SOX2, PFDN5, MYC, EP300, CDK2, CCNE1, CCNB1, CCNA2, CCND1, XPO1, PIN1, AURKA, PRKACA, MAD2L1, HSPA9, CDC20, TP53BP1, RBX1, DDB1, RCHY1, KAT2B, NEDD8, MDM2, IKBKB, DAXX, CHUK, BUB1B, BRCA1, TNK2, AMPH, CREBBP, KAT5, CEP131, MD
Protein Size: 636 - 
                                            
Molekulargewicht
 - 69 kDa
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Gen-ID
 - 7161
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NCBI Accession
 - NM_005427, NP_005418
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UniProt
 - O15350
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Pathways
 - Regulation of Cell Size, Positive Regulation of Response to DNA Damage Stimulus
 
Target
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