TBX3 Antikörper (T-Box 3) (Middle Region)

Details for Product anti-TBX3 Antibody No. ABIN2777925, Anbieter: Anmelden zum Anzeigen
Antigen
  • xtbx3
  • ums
  • xhl
  • tbx3-iso
  • TBX3
  • TBX3-ISO
  • UMS
  • XHL
  • D5Ertd189e
  • T-box 3
  • T-box 3 S homeolog
  • TBX3
  • tbx3.S
  • tbx3
  • Tbx3
Epitop
Middle Region
15
14
11
10
8
7
7
4
4
3
2
2
2
2
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Human, Maus, Kaninchen, Ratte (Rattus)
81
33
31
6
5
4
4
4
3
2
2
2
Wirt
Kaninchen
79
12
2
Klonalität
Polyklonal
Konjugat
Dieser TBX3 Antikörper ist unkonjugiert
10
6
3
2
2
2
Applikation
Western Blotting (WB)
89
50
15
8
8
6
3
3
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human TBX3
Sequenz CRDKGSPAVK AHLFAAERPR DSGRLDKASP DSRHSPATIS SSTRGLGAEE
Homologie Cow: 100%, Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against TBX3. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Protein A purified
Plasmids, Primers & others Plasmide, Primers & weitere TBX3 products on genomics-online (e.g. as negative or positive controls)
Andere Bezeichnung TBX3 (TBX3 Antibody Abstract)
Hintergrund TBX3 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This protein is a transcriptional repressor and is thought to play a role in the anterior/posterior axis of the tetrapod forelimb. Mutations in this gene cause ulnar-mammary syndrome, affecting limb, apocrine gland, tooth, hair, and genital development. Alternative splicing of this gene results in three transcript variants encoding different isoforms, however, the full length nature of one variant has not been determined.
Alias Symbols: UMS, XHL, TBX3-ISO
Protein Interaction Partner: CA8, AES, SOX2, Dlg4, ELAVL1, HDAC5, HDAC3, HDAC2, HDAC1, TOLLIP, TBX3,
Protein Size: 600
Molekulargewicht 66 kDa
Gen-ID 6926
Pathways Hormone Transport, Stem Cell Maintenance, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Applikations-hinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 600 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-T-Box 3 (TBX3) (Middle Region) antibody (ABIN2777925) WB Suggested Anti-TBX3 Antibody Titration: 1.25ug/ml Positive Control: HepG2 cell ...
Western Blotting (WB) image for anti-T-Box 3 (TBX3) (Middle Region) antibody (ABIN2777925) Sample Type: human iPS cells and 293T cell lysatePrimary Dilution: 1.25ug/mL
Western Blotting (WB) image for anti-T-Box 3 (TBX3) (Middle Region) antibody (ABIN2777925) Sample Type: human iPS cells and 293T cell lysatePrimary Dilution: 1.25ug/mL
Produkt verwendet in: Bozyk, Popova, Bentley, Goldsmith, Linn, Weiss, Hershenson: "Mesenchymal stromal cells from neonatal tracheal aspirates demonstrate a pattern of lung-specific gene expression." in: Stem cells and development, Vol. 20, Issue 11, pp. 1995-2007, 2011 (PubMed).

Yano, Yamazaki, Adachi, Okawa, Fort, Uji, Tsukita, Tsukita: "Tara up-regulates E-cadherin transcription by binding to the Trio RhoGEF and inhibiting Rac signaling." in: The Journal of cell biology, Vol. 193, Issue 2, pp. 319-32, 2011 (PubMed).

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