T-Box 6 Antikörper (N-Term)

Produktnummer ABIN2777918

Der Kaninchen Polyklonal Anti-T-Box 6-Antikörper wurde für WB und IHC validiert. Er ist geeignet, T-Box 6 in Proben von Human, Maus, Ratte, Pferd, Schwein, Rind (Kuh), Hund und Meerschweinchen zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für T-Box 6 Antikörper (N-Term) (ABIN2777918)

Target: T-Box 6 (TBX6)

Reaktivität: Human, Maus, Ratte, Pferd, Schwein, Rind (Kuh), Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser T-Box 6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-T-Box 6 Antikörper

Bindungsspezifität: N-Term

Sequenz: AHPPLPLLPP AMGTEPAPSA PEALHSLPGV SLSLENRELW KEFSSVGTEM

Homologie: Cow: 92%, Dog: 92%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against TBX6. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TBX6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 436 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-T-Box 6 Antikörper (ABIN2777918)

Chen, Liu, Zhou, Hu, Fei, Xie, Ding: "Smad6 inhibits the transcriptional activity of Tbx6 by mediating its degradation." in: The Journal of biological chemistry, Vol. 284, Issue 35, pp. 23481-90, (2009) (PubMed).

Leschik, Stefanovic, Brinon, Pucéat: "Cardiac commitment of primate embryonic stem cells." in: Nature protocols, Vol. 3, Issue 9, pp. 1381-7, (2008) (PubMed).

Details zu T-Box 6

Target: T-Box 6 (TBX6)

Andere Bezeichnung: TBX6

Hintergrund: The TBX6 gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. TBX6 is the human ortholog of mouse Tbx6. Knockout experiments in mice indicate that Tbx6 is important for specification of paraxial mesoderm structures.
Alias Symbols: DFNB67
Protein Interaction Partner: HSFY1, C1orf94, RBPMS, TOX4, PSMA3, MEOX2, PRMT1,
Protein Size: 436

Molekulargewicht: 47 kDa

Gen-ID: 6911

NCBI Accession: NM_004608, NP_004599

UniProt: O95947