FLJ11730 (N-Term) Antikörper

Produktnummer ABIN2777884

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch in IHC und WB. Er zeigt eine Reaktivität gegenüber Human, Rind (Kuh), Maus, Ratte und Zebrafisch (Danio rerio).

Kurzübersicht für FLJ11730 (N-Term) Antikörper (ABIN2777884)

Target: FLJ11730

Reaktivität: Human, Rind (Kuh), Maus, Ratte, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Produktdetails

Bindungsspezifität: N-Term

Sequenz: HNKAAPPQIP DTRRELAELV KRKQELAETL ANLERQIYAF EGSYLEDTQM

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against FLJ11730. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FLJ11730

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 201 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: FLJ11730

Hintergrund: The screening of cDNA expression libraries from human tumors with serum antibody (SEREX) has proven to be a powerful method for identifying the repertoire of tumor antigens recognized by the immune system of cancer patients, referred to as the cancer immunome. In this regard, cancer/testis (CT) antigens are of particular interest because of their immunogenicity and restricted expression patterns. Synoivial sarcomas are striking with regard to CT antigen expression, however, highly expressed in sarcoma, CT antigens do not induce frequent humoral immune responses in sarcoma patients. Sera from two patients were used to immunoscreen cDNA libraries from two synovial sarcoma cell lines and normal testis, resulting in the identification of 113 distinct antigens. Sarcoma antigen NY-SAR-91 is one of them.
Alias Symbols: Eaf6, CENP-28, C1orf149, CDABP0189, NY-SAR-91, RP3-423B22.2, FLJ11730
Protein Interaction Partner: PLEKHF2, TRIM54, LDOC1, UBC, FXR2, H2AFZ, ELAVL1, SUMO2, JADE1, KAT5, tat, MRGBP, ING5, KAT6A, BRPF1, CCDC85B, L3MBTL2, ING3, ING4, KAT7,
Protein Size: 201

Molekulargewicht: 23 kDa

Gen-ID: 64769

NCBI Accession: NM_022756, NP_073593

UniProt: Q86WE3