BAF53A Antikörper (N-Term)

Produktnummer ABIN2777881

Dieses Anti-BAF53A-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BAF53A in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen und Meerschweinchen.

Kurzübersicht für BAF53A Antikörper (N-Term) (ABIN2777881)

Target: BAF53A (Actin-Like 6A (BAF53A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Kaninchen, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAF53A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-BAF53A Antikörper

Bindungsspezifität: N-Term

Sequenz: VDFPTAIGMV VERDDGSTLM EIDGDKGKQG GPTYYIDTNA LRVPRENMEA

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ACTL6A. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ACTL6A

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 429 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu BAF53A

Target: BAF53A (Actin-Like 6A (BAF53A))

Andere Bezeichnung: ACTL6A

Hintergrund: This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila, the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Alias Symbols: ACTL6, BAF53A, MGC5382, Arp4, INO80K, ARPN-BETA
Protein Interaction Partner: UBC, BMI1, HECW2, FBXO6, HDAC2, CBX5, UCHL5, ARID1B, RUVBL1, TRRAP, ARID1A, SMARCE1, SMARCC2, SMARCC1, SMARCA4, SMARCA2, UBD, GRB2, INO80E, CAND1, CUL3, CDK9, CDK2, H2AFZ, TP53, UL27, SMARCD1, HDGF, SOX2, SMARCAD1, KAT5, PBRM1, Bcl7b, INO80C, ACTR8, INO80
Protein Size: 429

Molekulargewicht: 47 kDa

Gen-ID: 86

NCBI Accession: NM_004301, NP_004292

UniProt: O96019

Pathways: Chromatin Binding, Photoperiodism