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EPC1 Antikörper (Middle Region)

EPC1 Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Ratte, Meerschweinchen, Schwein WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2777875
  • Target Alle EPC1 Antikörper anzeigen
    EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))
    Bindungsspezifität
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 19
    • 16
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Ratte, Meerschweinchen, Schwein
    Wirt
    • 18
    • 3
    Kaninchen
    Klonalität
    • 20
    • 1
    Polyklonal
    Konjugat
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser EPC1 Antikörper ist unkonjugiert
    Applikation
    • 11
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    VNKQDKADLI RPKRKYEKKP KVLPSSAAAT PQQTSPAALP VFNAKDLNQY
    Homologie
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EPC1. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human EPC1
    Top Product
    Discover our top product EPC1 Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 836 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))
    Andere Bezeichnung
    EPC1 (EPC1 Produkte)
    Synonyme
    EPC1 antikoerper, Epl1 antikoerper, 2400007E14Rik antikoerper, 5730566F07Rik antikoerper, A930032N02Rik antikoerper, epc1 antikoerper, enhancer of polycomb homolog 1 antikoerper, enhancer of polycomb homolog 1 (Drosophila) a antikoerper, enhancer of polycomb homolog 1 (Drosophila) antikoerper, enhancer of polycomb homolog 1 L homeolog antikoerper, EPC1 antikoerper, epc1a antikoerper, Epc1 antikoerper, epc1 antikoerper, epc1.L antikoerper
    Hintergrund
    EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
    Alias Symbols: DKFZp781P2312, Epl1
    Protein Interaction Partner: RINT1, KRT15, Hopx, TRIM27, H2AFZ, DMAP1, ING3, MORF4L1, KAT5, MYC, MORF4L2, MRGBP, EED, EZH2, E2F6, SRF,
    Protein Size: 836
    Molekulargewicht
    93 kDa
    Gen-ID
    80314
    NCBI Accession
    NM_025209, NP_079485
    UniProt
    Q9H2F5
    Pathways
    Regulation of Muscle Cell Differentiation
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