EPC1 Antikörper (Middle Region)

Produktnummer ABIN2777875

Der Kaninchen Polyklonal Anti-EPC1-Antikörper wurde für WB validiert. Er ist geeignet, EPC1 in Proben von Human, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Ratte, Meerschweinchen und Schwein zu detektieren.

Kurzübersicht für EPC1 Antikörper (Middle Region) (ABIN2777875)

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Pferd, Kaninchen, Ratte, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EPC1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: VNKQDKADLI RPKRKYEKKP KVLPSSAAAT PQQTSPAALP VFNAKDLNQY

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against EPC1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human EPC1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 836 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu EPC1

Target: EPC1 (Enhancer of Polycomb Homolog 1 (EPC1))

Andere Bezeichnung: EPC1

Hintergrund: EPC1 is a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Alias Symbols: DKFZp781P2312, Epl1
Protein Interaction Partner: RINT1, KRT15, Hopx, TRIM27, H2AFZ, DMAP1, ING3, MORF4L1, KAT5, MYC, MORF4L2, MRGBP, EED, EZH2, E2F6, SRF,
Protein Size: 836

Molekulargewicht: 93 kDa

Gen-ID: 80314

NCBI Accession: NM_025209, NP_079485

UniProt: Q9H2F5

Pathways: Regulation of Muscle Cell Differentiation