SLUG Antikörper (Middle Region)

Produktnummer ABIN2777851

Dieses Anti-SLUG-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SLUG in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Kaninchen, Meerschweinchen und Saccharomyces cerevisiae.

Kurzübersicht für SLUG Antikörper (Middle Region) (ABIN2777851)

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schaf, Hund, Pferd, Kaninchen, Meerschweinchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLUG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-SLUG Antikörper

Bindungsspezifität: Middle Region

Sequenz: SDTSSKDHSG SESPISDEEE RLQSKLSDPH AIEAEKFQCN LCNKTYSTFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Yeast: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SNAI2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SNAI2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 268 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SLUG

Target: SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))

Andere Bezeichnung: SNAI2

Hintergrund: SNAI2 is a member of the Snail family of C2H2-type zinc finger transcription factors. The protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC10182, SLUG, SLUGH1, WS2D, SNAIL2
Protein Interaction Partner: SAT1, TRIM23, PPP2R2D, PPP6R3, STUB1, TJP2, UBC, TP53, PSMD3, PSMD1, PSMC1, PSMA3, PPP2CB, GSK3B, MDM2, APP, KDM1A, HDAC1, CHD4, Sin3a, HDAC2,
Protein Size: 268

Molekulargewicht: 30 kDa

Gen-ID: 6591

NCBI Accession: NM_003068, NP_003059

UniProt: O43623