SIAH2 Antikörper (Middle Region)

Produktnummer ABIN2777843

Produktdetails anti-SIAH2 Antikörper

Target: SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SIAH2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: AVDWVMMQSC FGHHFMLVLE KQEKYEGHQQ FFAIVLLIGT RKQAENFAYR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SIAH2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SIAH2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 324 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SIAH2

Target: SIAH2 (Siah E3 Ubiquitin Protein Ligase 2 (SIAH2))

Andere Bezeichnung: SIAH2 (SIAH2 Produkte)

Synonyme: hSiah2 antikoerper, Xsiah-2 antikoerper, siah2-A antikoerper, xsiah2 antikoerper, AA415433 antikoerper, Sinh2 antikoerper, siah E3 ubiquitin protein ligase 2 antikoerper, siah E3 ubiquitin protein ligase 2 L homeolog antikoerper, seven in absentia 2 antikoerper, SIAH2 antikoerper, siah2.L antikoerper, Siah2 antikoerper

Hintergrund: SIAH2 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia.This gene encodes a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in regulating cellular response to hypoxia. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: hSiah2
Protein Interaction Partner: EGLN3, XAF1, HIPK2, UBE2D1, UBE2L6, SIAH2, UBE2D3, UBC, PPP1R13B, TP53BP2, NFE2L2, USP19, AR, UBE2I, STAT3, MYD88, EEF1D, CCBE1, SETD2, HIPK3, TNK2, KAT5, KAT2B, UBE2D2, TPX2, PML, ATN1, PSMD4, PPP1R12A, EGLN2, SH3RF1, EGLN1, DYRK2, PPP1CC, AFF1, DCC, CEB
Protein Size: 324

Molekulargewicht: 34 kDa

Gen-ID: 6478

NCBI Accession: NM_005067, NP_005058

UniProt: O43255