PRDM12 Antikörper (N-Term)

Produktnummer ABIN2777809

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PRDM12 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Zebrafisch (Danio rerio) und Meerschweinchen.

Kurzübersicht für PRDM12 Antikörper (N-Term) (ABIN2777809)

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Zebrafisch (Danio rerio), Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PRDM12 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: PRDM12 Antibody - N-terminal region

Sequenz: SFLYGRWRNV LGEQLFEDKS HHASPKTAFT AEVLAQSFSG EVQKLSSLVL

Homologie: Cow: 100%, Dog: 91%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP33218-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu PRDM12

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Andere Bezeichnung: PRDM12

Hintergrund:

Background Information: PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.

Gene Name: PR domain containing 12

Alternative Symbols: PFM9, HSAN8

Protein Name: PR domain zinc finger protein 12

Molekulargewicht: 40kDa

Gen-ID: 59335

NCBI Accession: NP_067632

UniProt: Q9H4Q4