PRDM12 Antikörper (N-Term)

Produktnummer ABIN2777809

Produktdetails anti-PRDM12 Antikörper

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Schwein, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PRDM12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SFLYGRWRNV LGEQLFEDKS HHASPKTAFT AEVLAQSFSG EVQKLSSLVL

Homologie: Cow: 100%, Dog: 91%, Guinea Pig: 92%, Human: 100%, Mouse: 92%, Pig: 100%, Rat: 92%, Zebrafish: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against PRDM12. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PRDM12

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 367 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PRDM12

Target: PRDM12 (PR Domain Containing 12 (PRDM12))

Andere Bezeichnung: PRDM12 (PRDM12 Produkte)

Synonyme: PRDM12 antikoerper, prdm12 antikoerper, MGC146714 antikoerper, PFM9 antikoerper, pfm9 antikoerper, Gm998 antikoerper, PR/SET domain 12 antikoerper, PR domain containing 12 antikoerper, PR domain containing 12 L homeolog antikoerper, PR domain containing 12a antikoerper, PRDM12 antikoerper, prdm12 antikoerper, prdm12.L antikoerper, Prdm12 antikoerper, prdm12a antikoerper

Hintergrund: PRDM12 belongs to PR-domain family which are involved in human cancers in an unusual yin-yang fashion. Two products are normally produced from a PR-domain family member which differ by the presence or absence of the PR domain, the PR-plus product is disrupted or underexpressed whereas the PR-minus product is present or overexpressed in cancer cells. This imbalance in the amount of the two products, a result of either genetic or epigenetic events, appears to be an important cause of malignancy. PRDM12 may have a potential role in the pathogenesis of chronic myeloid leukaemia with derivative chromosome 9 deletion.
Alias Symbols: PFM9
Protein Size: 367

Molekulargewicht: 40 kDa

Gen-ID: 59335

NCBI Accession: NM_021619, NP_067632

UniProt: Q9H4Q4