MTA3 Antikörper (N-Term)

Produktnummer ABIN2777793

Der Kaninchen Polyklonal Anti-MTA3-Antikörper wurde für WB validiert. Er ist geeignet, MTA3 in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen und Hund zu detektieren.

Kurzübersicht für MTA3 Antikörper (N-Term) (ABIN2777793)

Target: MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-MTA3 Antikörper

Bindungsspezifität: N-Term

Sequenz: TLIMLADKHA KEIEEESETT VEADLTDKQK HQLKHRELFL SRQYESLPAT

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against MTA3. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human MTA1

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MTA3

Target: MTA3 (Metastasis Associated 1 Family, Member 3 (MTA3))

Andere Bezeichnung: MTA3

Hintergrund: This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene.
Protein Size: 392

Molekulargewicht: 43 kDa

Gen-ID: 9112

NCBI Accession: NM_001203258, NP_001190187

Pathways: Chromatin Binding