IVNS1ABP Antikörper (N-Term)
Kurzübersicht für IVNS1ABP Antikörper (N-Term) (ABIN2777748)
Target
Alle IVNS1ABP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- RAVLACCSPY LFEIFNSDSD PHGISHVKFD DLNPEAVEVL LNYAYTAQLK
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Homologie
- Cow: 86%, Dog: 100%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 92%, Pig: 100%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%
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Produktmerkmale
- This is a rabbit polyclonal antibody against IVNS1ABP. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human IVNS1ABP
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 642 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IVNS1ABP (Influenza Virus NS1A Binding Protein (IVNS1ABP))
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Andere Bezeichnung
- IVNS1ABP
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Substanzklasse
- Influenza Protein
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Hintergrund
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This gene encodes a protein which interacts with the nonstructural NS1 protein of the influenza A virus. In noninfected cells, affinity-purified antibodies localized this protein in nuclear regions enriched with the spliceosome assembly factor SC35, suggesting an association with the cellular splicing apparatus. In influenza A virus-infected cells, the protein relocalized throughout the nucleoplasm and appeared distinct from the SC35 domains, which suggests that its function may be disturbed or altered.
Alias Symbols: ND1, NS-1, NS1BP, FLARA3, KLHL39, NS1-BP, HSPC068
Protein Interaction Partner: UBC, DHX36, PARP1, ACTB, ZC3HAV1, RBMX, LARP1, DHX30, HNRNPUL1, IGF2BP1, IVNS1ABP, DDX17, HNRNPR, LRPPRC, THRAP3, G3BP2, DDX21, PABPC4, GBF1, STAU1, UPF1, POLR2A, YBX1, NCBP1, HNRNPM, MYH9, ILF3, ILF2, HSP90AB1, HSPA8, HNRNPU, HNRNPL, HNRNPK, HNRNPF, HNRN
Protein Size: 642 -
Molekulargewicht
- 72 kDa
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Gen-ID
- 10625
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NCBI Accession
- NM_006469, NP_006460
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UniProt
- Q9Y6Y0
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Pathways
- Negative Regulation of intrinsic apoptotic Signaling
Target
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